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Connexin 43/GJA1 antibody (C-Term)

GJA1 Reactivity: Human, Rat, Mouse, Dog, Monkey, Cow, Rabbit, Guinea Pig, Pig, Hamster, Gorilla, Gibbon IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2469543
  • Target See all Connexin 43/GJA1 (GJA1) Antibodies
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Binding Specificity
    • 20
    • 16
    • 15
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 134
    • 92
    • 90
    • 32
    • 11
    • 11
    • 11
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog, Monkey, Cow, Rabbit, Guinea Pig, Pig, Hamster, Gorilla, Gibbon
    Host
    • 129
    • 8
    • 4
    • 1
    Rabbit
    Clonality
    • 133
    • 8
    Polyclonal
    Conjugate
    • 82
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    Application
    • 98
    • 53
    • 48
    • 29
    • 21
    • 16
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC)
    Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    GJA1 antibody was raised against a peptide located in the C-Terminal domain of GJA1 (Human).
    Top Product
    Discover our top product GJA1 Primary Antibody
  • Application Notes
    GJA1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, immunocytochemistry, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry starting at 1 - 2 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-80 °C
    Storage Comment
    GJA1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • Target
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Alternative Name
    GJA1 (GJA1 Products)
    Synonyms
    AVSD3 antibody, CX43 antibody, DFNB38 antibody, GJAL antibody, HLHS1 antibody, HSS antibody, ODDD antibody, Cx43 antibody, AU042049 antibody, AW546267 antibody, Cnx43 antibody, Cx43alpha1 antibody, Gja-1 antibody, Npm1 antibody, connexin43 antibody, cx43a1 antibody, gja1 antibody, zfCx43.3 antibody, connexin 43 antibody, gja1-A antibody, cx43 antibody, gjal antibody, oddd antibody, dfnb38 antibody, gap junction protein alpha 1 antibody, gap junction protein, alpha 1 antibody, connexin 43 antibody, gap junction protein alpha 1 L homeolog antibody, CONNEXIN 43 protein antibody, GJA1 antibody, Gja1 antibody, cx43 antibody, gja1.L antibody, gja1 antibody, CONNEXIN 43 antibody
    Background
    Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
    Gene ID
    2697
    UniProt
    P17302
    Pathways
    MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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