TBK1 antibody (AA 563-577)

Catalog No. ABIN2469637

Product Details anti-TBK1 Antibody

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Binding Specificity: AA 563-577

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Pig, Rabbit, Horse, Hamster, Gibbon, Gorilla

Host: Mouse

Clonality: Monoclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein G Column

Immunogen: TBK1 monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 563 - 577 of TBK1 (Human).

Clone: 108A429

Isotype: IgG1 kappa

Application Details

Application Notes: TBK1 antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: TBK1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1 (TBK1 Products)

Synonyms: nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody

Background: TBK1, also known as NF-kappa-B-activating kinase (NAK), is an IKAPPAB type protein kinase. TBK1 protein contains a N-terminal kinase domain and two putative coiled-coil regions in the C-terminal region. It has been shown to associate with TANK and TRAF2 in a TBK1-TANK-TRAF2 signaling complex, which is believed to function upstream of the IKK complex in the TRAF-mediated activation of NF-kappaB.

Gene ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome