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CDK2 antibody
CDK2
Reactivity: Human, Mouse, Xenopus laevis
WB, IHC, ELISA, IP
Host: Mouse
Monoclonal
unconjugated
Product Details anti-CDK2 Antibody
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Target
See all CDK2 Antibodies
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Reactivity
All reactivities for CDK2 antibodies
Human, Mouse, Xenopus laevis
Host
All hosts for CDK2 antibodies
Mouse
Clonality
All clonalities for CDK2 antibodies
Monoclonal
Conjugate
All conjugates for CDK2 antibodies
This CDK2 antibody is un-conjugated
Application
All applications for CDK2 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
Specificity
Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.
Purification
Protein G Column
Immunogen
CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).
Isotype
IgG
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Discover our top product CDK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store CDK2 antibody at 4 °C or -20 °C.
Target Details for CDK2
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Target
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Alternative Name
CDK2 (CDK2 Products )
Synonyms
p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
Background
Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.
Gene ID
1017
UniProt
P24941
Pathways
PI3K-Akt Signaling , Cell Division Cycle , Mitotic G1-G1/S Phases , DNA Replication , M Phase , Synthesis of DNA
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