GZMB antibody (C-Term)

Catalog No. ABIN2470728

This anti-GZMB antibody is a Rabbit Polyclonal antibody detecting GZMB in IHC. Suitable for Human, Mouse and Rat.

Quick Overview for GZMB antibody (C-Term) (ABIN2470728)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMB antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-GZMB Antibody

Binding Specificity: C-Term

Purification: Immunoaffinity Chromatography

Immunogen: GZMB antibody was raised against amino acids from the C-Terminus of Granzyme B (Human)

Application Details

Application Notes: GZMB antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, BSA, sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store GZMB antibody at 4 °C or -20 °C.

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: GZMB

Background: Granzyme A and granzyme B are serine proteases that mediate apoptotic signaling in cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. Both granzyme A and granzyme B are synthesized as inactive proenzymes, and they are stored within cytolytic granules and released by effector cells during degradation. This antibody should be useful for the localization of granzyme B-containing lytic granules and for the characterization of activated CTLs or NK cells.

Gene ID: 3002

UniProt: P10144

Pathways: Apoptosis, Caspase Cascade in Apoptosis