PRKDC antibody

Catalog No. ABIN2473350

Cited in 2+ publications. The Rabbit Polyclonal anti-PRKDC antibody (ABIN2473350) specifically detects PRKDC in WB, IP, IHC (p) and EMSA. The antibody is reactive with Human, Mouse, Rat and Hamster samples.

Quick Overview for PRKDC antibody (ABIN2473350)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKDC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Electrophoretic Mobility-Shift Assay (EMSA)

Product Details anti-PRKDC Antibody

Cross-Reactivity: Hamster, Mouse (Murine), Rat (Rattus)

Characteristics: Serum

Immunogen: Human DNA-PKcs fragment

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

References for anti-PRKDC antibody (ABIN2473350)

Hoek, Myers, Stillman: "An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10876-87, (2011) (PubMed).

Jayaram, Gilson, Ehrlich, Yu, Ketner, Hanakahi: "E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection." in: Virology, Vol. 382, Issue 2, pp. 163-70, (2008) (PubMed).

Target Details for PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: DNA PKcs

Gene ID: 5591

UniProt: P78527

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response