ErbB2/Her2 antibody

Catalog No. ABIN2473977

Cited in 1 publication. The Rat Monoclonal anti-ErbB2/Her2 antibody (Clone ICR55) (ABIN2473977) specifically detects ErbB2/Her2 in WB, FACS, IHC (p), IP and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for ErbB2/Her2 antibody (ABIN2473977)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This ErbB2/Her2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ICR55

Product Details anti-ErbB2/Her2 Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-ErbB2/Her2 antibody (ABIN2473977)

Sain, Krishnan, Ormerod, De Rienzo, Liu, Kaye, Workman, Jackman: "Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT." in: Molecular cancer therapeutics, Vol. 5, Issue 5, pp. 1197-208, (2006) (PubMed).

Target Details for ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Alternative Name: HER2/neu

Background: Synonyms: CD340

Gene ID: 2064

UniProt: P04626

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development