This Mouse Monoclonal antibody specifically detects Notch1 in FACS. It exhibits reactivity toward Human and Mouse. It has been mentioned in 2+ publications
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Espinosa, Santos, Inglés-Esteve, Muñoz-Canoves, Bigas: "p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR." in: Journal of cell science, Vol. 115, Issue Pt 6, pp. 1295-303, (2002) (PubMed).
Huppert, Le, Schroeter, Mumm, Saxena, Milner, Kopan: "Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1." in: Nature, Vol. 405, Issue 6789, pp. 966-70, (2000) (PubMed).