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p53 antibody (AA 181-190)

There are 2+ publications for this product available. The Mouse Monoclonal anti-p53 antibody is suitable to detect p53 in samples from Human. It has been validated for WB, IHC (p), IP and IHC (fro).
Catalog No. ABIN2476010
$514.46
Plus shipping costs $50.00
0.1 mg
Shipping to: United States
Delivery in 3 to 5 Business Days

Quick Overview for p53 antibody (AA 181-190) (ABIN2476010)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

  • 1056
  • 341
  • 270
  • 140
  • 75
  • 74
  • 54
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Human

Host

  • 792
  • 292
  • 3
  • 3
  • 2
  • 2
Mouse

Clonality

  • 584
  • 509
  • 1
Monoclonal

Conjugate

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  • 31
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  • 11
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  • 11
  • 11
  • 2
  • 2
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  • 1
  • 1
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This p53 antibody is un-conjugated

Application

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  • 64
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  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

DO-11
  • Binding Specificity

    • 48
    • 39
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    • 36
    • 34
    • 32
    • 31
    • 30
    • 27
    • 27
    • 27
    • 23
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    • 3
    AA 181-190

    Characteristics

    Purified IgG

    Purification

    Purified

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL
  • Palecek, Brázdová, Brázda, Palecek, Billová, Subramaniam, Jovin: "Binding of p53 and its core domain to supercoiled DNA." in: European journal of biochemistry / FEBS, Vol. 268, Issue 3, pp. 573-81, (2001) (PubMed).

    Coomber, Ward: "Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 9, pp. 2802-8, (2001) (PubMed).

  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    p53

    Gene ID

    7157

    UniProt

    P04637

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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