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p53 antibody (AA 181-190)

The Mouse Monoclonal anti-p53 antibody has been validated for WB, IHC (p), IP and IHC (fro). It is suitable to detect p53 in samples from Human. There are 2+ publications available.
Catalog No. ABIN2476010

Quick Overview for p53 antibody (AA 181-190) (ABIN2476010)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

  • 957
  • 277
  • 229
  • 140
  • 74
  • 72
  • 57
  • 39
  • 10
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  • 6
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  • 1
  • 1
Human

Host

  • 671
  • 312
  • 5
  • 2
  • 2
Mouse

Clonality

  • 576
  • 415
  • 1
Monoclonal

Conjugate

  • 519
  • 51
  • 31
  • 20
  • 19
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 14
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  • 14
  • 12
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  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This p53 antibody is un-conjugated

Application

  • 726
  • 322
  • 287
  • 238
  • 210
  • 140
  • 129
  • 126
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  • 80
  • 59
  • 32
  • 20
  • 17
  • 12
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  • 3
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  • 2
  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

DO-11
  • Binding Specificity

    • 39
    • 38
    • 38
    • 31
    • 31
    • 30
    • 26
    • 26
    • 24
    • 22
    • 21
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    • 19
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    • 16
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    • 4
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    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    AA 181-190

    Characteristics

    Purified IgG

    Purification

    Purified

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL
  • Palecek, Brázdová, Brázda, Palecek, Billová, Subramaniam, Jovin: "Binding of p53 and its core domain to supercoiled DNA." in: European journal of biochemistry / FEBS, Vol. 268, Issue 3, pp. 573-81, (2001) (PubMed).

    Coomber, Ward: "Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 9, pp. 2802-8, (2001) (PubMed).

  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    p53

    Gene ID

    7157

    UniProt

    P04637

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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