TNF alpha antibody

Catalog No. ABIN2476860

Cited in 3+ publications. The Mouse Monoclonal anti-TNF alpha antibody (Clone CC327) (ABIN2476860) specifically detects TNF alpha in ELISA and FACS. The antibody is reactive with Cow and Deer samples.

Quick Overview for TNF alpha antibody (ABIN2476860)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Cow, Deer

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: CC327

Product Details anti-TNF alpha Antibody

Cross-Reactivity: Dama mesopotamica (Mesopotamian fallow deer)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Recombinant bovine TNF alpha

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TNF alpha antibody (ABIN2476860)

Guergnon, Chaussepied, Sopp, Lizundia, Moreau, Blumen, Werling, Howard, Langsley: "A tumour necrosis factor alpha autocrine loop contributes to proliferation and nuclear factor-kappaB activation of Theileria parva-transformed B cells." in: Cellular microbiology, Vol. 5, Issue 10, pp. 709-16, (2003) (PubMed).

Hope, Whelan, Hewinson, Vordermeier, Howard: "Maturation of bovine dendritic cells by lipopeptides." in: Veterinary immunology and immunopathology, Vol. 95, Issue 1-2, pp. 21-31, (2003) (PubMed).

Whelan, Hope, Howard, Clifford, Hewinson, Vordermeier: "Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide." in: Infection and immunity, Vol. 71, Issue 11, pp. 6420-5, (2003) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Gene ID: 280943

UniProt: Q06599

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome