TNF alpha antibody

Catalog No. ABIN2476864

This Mouse Monoclonal antibody specifically detects TNF alpha in ELISA. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for TNF alpha antibody (ABIN2476864)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: ELISA

Clone: B-C7

Product Details anti-TNF alpha Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TNF alpha antibody (ABIN2476864)

Limb, Daniels, Pleass, Charteris, Luthert, Khaw: "Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha." in: The American journal of pathology, Vol. 160, Issue 5, pp. 1847-55, (2002) (PubMed).

Hamacher, Lucas, Lijnen, Buschke, Dunant, Wendel, Grau, Suter, Ricou: "Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome." in: American journal of respiratory and critical care medicine, Vol. 166, Issue 5, pp. 651-6, (2002) (PubMed).

Musey, Ding, Cao, Lee, Galloway, Yuen, Jerome, McElrath: "Ontogeny and specificities of mucosal and blood human immunodeficiency virus type 1-specific CD8(+) cytotoxic T lymphocytes." in: Journal of virology, Vol. 77, Issue 1, pp. 291-300, (2002) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Gene ID: 7124

UniProt: P01375

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome