TNF alpha antibody

Catalog No. ABIN2476868

The Mouse Monoclonal anti-TNF alpha antibody has been validated for WB, FACS and IHC (fro). It is suitable to detect TNF alpha in samples from Cow, Sheep and Water Buffalo. There are 2+ publications available.

Quick Overview for TNF alpha antibody (ABIN2476868)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Cow, Sheep, Water Buffalo

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: VPM61

Product Details anti-TNF alpha Antibody

Cross-Reactivity: Cow (Bovine), Water buffalo (Bubalus bubalis)

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-TNF alpha antibody (ABIN2476868)

Kwong, Thom, Sopp, Rocchi, Wattegedera, Entrican, Hope: "Production and characterization of two monoclonal antibodies to bovine tumour necrosis factor alpha (TNF-alpha) and their cross-reactivity with ovine TNF-alpha." in: Veterinary immunology and immunopathology, Vol. 135, Issue 3-4, pp. 320-4, (2010) (PubMed).

Sow, Gallup, Olivier, Krishnan, Patera, Suzich, Ackermann: "Respiratory syncytial virus is associated with an inflammatory response in lungs and architectural remodeling of lung-draining lymph nodes of newborn lambs." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 1, pp. L12-24, (2010) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Gene ID: 443540

UniProt: P23383

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome