TNF alpha antibody

Catalog No. ABIN2476877

The Rabbit Polyclonal anti-TNF alpha antibody has been validated for WB, ELISA, IHC (p) and Func. It is suitable to detect TNF alpha in samples from Rat. There are 3+ publications available.

Quick Overview for TNF alpha antibody (ABIN2476877)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Product Details anti-TNF alpha Antibody

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1.0 mg/mL

References for anti-TNF alpha antibody (ABIN2476877)

Sandoval, Pereda, Rodriguez, Escobar, Hidalgo, Joosten, Franco, Sastre, López-Rodas: "Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 10, pp. 1687-97, (2010) (PubMed).

Halin, Rudolfsson, Doll, Crawford, Wikström, Bergh: "Pigment epithelium-derived factor stimulates tumor macrophage recruitment and is downregulated by the prostate tumor microenvironment." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 4, pp. 336-45, (2010) (PubMed).

Khandelwal, Dumanis, Feng, Maguire-Zeiss, Rebeck, Lashuel, Moussa: "Parkinson-related parkin reduces ?-Synuclein phosphorylation in a gene transfer model." in: Molecular neurodegeneration, Vol. 5, pp. 47, (2010) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Gene ID: 24835

UniProt: P16599

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome