Aurora A antibody

Catalog No. ABIN2477554

This Mouse Monoclonal antibody specifically detects Aurora A in WB, IF and IP. It exhibits reactivity toward Human and Mouse and has been mentioned in 3+ publications.

Quick Overview for Aurora A antibody (ABIN2477554)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 35C1

Product Details anti-Aurora A Antibody

Cross-Reactivity: Mouse (Murine)

Characteristics: Purified IgG

Purification: Purified

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-Aurora A antibody (ABIN2477554)

Hartsink-Segers, Zwaan, Exalto, Luijendijk, Calvert, Petricoin, Evans, Reinhardt, de Haas, Hedtjärn, Hansen, Koch, Caron, Pieters, Den Boer: "Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target." in: Leukemia, Vol. 27, Issue 3, pp. 560-8, (2013) (PubMed).

Hartsink-Segers, Exalto, Allen, Williamson, Clifford, Horstmann, Caron, Pieters, Den Boer: "Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells." in: Haematologica, Vol. 98, Issue 10, pp. 1539-46, (2013) (PubMed).

Cremet, Descamps, Vérite, Martin, Prigent: "Preparation and characterization of a human aurora-A kinase monoclonal antibody." in: Molecular and cellular biochemistry, Vol. 243, Issue 1-2, pp. 123-31, (2003) (PubMed).

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: AURORA-A KINASE

Background: Synonyms: SERINE/THREONINE KINASE 15

Gene ID: 6790

UniProt: O14965

Pathways: Cell Division Cycle, Asymmetric Protein Localization