CD11b antibody

Catalog No. ABIN2478233

The Rat Monoclonal anti-CD11b antibody has been validated for FACS, IP, IF, IHC (fro) and Func. It is suitable to detect CD11b in samples from Human and Mouse. There are 3+ publications available.

Quick Overview for CD11b antibody (ABIN2478233)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 5C6

Product Details anti-CD11b Antibody

Cross-Reactivity: Human

Characteristics: Purified IgG

Endotoxin Level: Low endotoxin

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

References for anti-CD11b antibody (ABIN2478233)

Engwerda, Mynott, Sawhney, De Souza, Bickle, Kaye: "Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria." in: The Journal of experimental medicine, Vol. 195, Issue 10, pp. 1371-7, (2002) (PubMed).

Platt, Suzuki, Kodama, Gordon: "Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 9, pp. 4861-7, (2000) (PubMed).

Serafini, Columba-Cabezas, Di Rosa, Aloisi: "Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis." in: The American journal of pathology, Vol. 157, Issue 6, pp. 1991-2002, (2000) (PubMed).

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: CD11b

Background: Synonyms: INTEGRIN ALPHA M CHAIN, MAC-1

Gene ID: 16409

UniProt: P05555

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation