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CCR5 antibody (pSer349)

CCR5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2567085
  • Target See all CCR5 Antibodies
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Binding Specificity
    • 16
    • 13
    • 12
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer349
    Reactivity
    • 139
    • 40
    • 39
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 104
    • 30
    • 13
    • 4
    Rabbit
    Clonality
    • 107
    • 38
    • 3
    Polyclonal
    Conjugate
    • 83
    • 15
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR5 antibody is un-conjugated
    Application
    • 95
    • 66
    • 55
    • 20
    • 19
    • 17
    • 16
    • 14
    • 14
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificity
    The antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349.
    Purification
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    Immunogen
    CCR5 (phospho Ser349) antibody was raised against a peptide sequence around phosphorylation site of Serine 349 (E-I-S (p)-V-G) derived from Human CCR5.
    Isotype
    IgG
    Top Product
    Discover our top product CCR5 Primary Antibody
  • Application Notes
    Western Blot: 1:500~1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store antibody at -20°C for up to one year.
  • Target
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Alternative Name
    CCR5 (CCR5 Products)
    Synonyms
    CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
    Background
    Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
    Molecular Weight
    40 kDa
    Gene ID
    1234, 727797
    NCBI Accession
    NP_000570
    UniProt
    P51681
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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