p21 antibody (pThr145)

Catalog No. ABIN2618951

This Rabbit Polyclonal antibody specifically detects p21 in WB, IHC, IF, IHC (p) and ICC. It exhibits reactivity toward Human, Sheep, Cow and Dog.

Quick Overview for p21 antibody (pThr145) (ABIN2618951)

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Reactivity: Human, Sheep, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-p21 Antibody

Binding Specificity: pThr145

Specificity: Recognizes endogenous levels of p21 (pT145) protein.

Purification: Immunoaffinity purified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human p21 (pT145).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ICC (1:100 - 1:500), IF, IHC, IHC-P (1:100 - 1:200), WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 0.01 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for p21

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Alternative Name: CDKN1A / WAF1 / p21

Background: Name/Gene ID: CDKN1A

Synonyms: CDKN1A, CDKN1, CIP1, CDK-interacting protein 1, DNA synthesis inhibitor, p21CIP1, MDA6, PIC1, SDI1, WAF1, CAP20, CDK-interaction protein 1, MDA-6, p21

Gene ID: 1026

Pathways: p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy