GZMB antibody (AA 21-247)

Catalog No. ABIN2621688

The Mouse Monoclonal anti-GZMB antibody has been validated for WB, IHC, IF and IHC (p). It is suitable to detect GZMB in samples from Human.

Quick Overview for GZMB antibody (AA 21-247) (ABIN2621688)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4E6

Product Details anti-GZMB Antibody

Binding Specificity: AA 21-247

Specificity: Human GZMB / Granzyme B

Purification: Immunoaffinity purified

Immunogen: Human recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: IF (1:100), IHC, IHC-P (1:150), WB (1:2000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 1 % BSA, 50 % glycerol, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: GZMB / Granzyme B

Background: Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease

Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

Gene ID: 3002

NCBI Accession: NP_004122

Pathways: Apoptosis, Caspase Cascade in Apoptosis