Lamin A/C antibody (pSer392)

Catalog No. ABIN2624916

The Rabbit Polyclonal anti-Lamin A/C antibody has been validated for WB, IHC, IF, IP, ICC and IHC (p). It is suitable to detect Lamin A/C in samples from Human, Mouse, Rat, Cow, Pig and Monkey.

Quick Overview for Lamin A/C antibody (pSer392) (ABIN2624916)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Lamin A/C Antibody

Binding Specificity: pSer392

Specificity: Recognizes endogenous levels of Lamin A/C (pS392) protein.

Purification: Immunoaffinity purified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Lamin A/C (pS392).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ICC (1:100 - 1:500), IF, IHC, IHC-P (1:100 - 1:200), IP (1:10 - 1:100), WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 0.01 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus