Lamin B1 antibody (AA 526-537)

Catalog No. ABIN2624917

Product Details anti-Lamin B1 Antibody

Target: Lamin B1 (LMNB1)

Binding Specificity: AA 526-537

Reactivity: Human, Cow, Dog, Rabbit, Pig, Horse, Xenopus laevis, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human LMNB1 / Lamin B1. This antibody is expected to recognize both reported isoforms (NP_005564.1, NP_001185486.1).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-DVKVILKNSQGE from an internal region (near C-terminus) of human LMNB1 / Lamin B1 (NP_005564.1, NP_001185486.1). Percent identity by BLAST analysis: Hamster, Panda, Bovine, Dog, Cat, Horse, Rabbit, Pig, Xenopus (100%), Galago, Rat, Guinea pig, Zebra finch, Chicken (92%), Lizard (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:64000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 70kD band observed in nuclear lysates of cell lines HeLa and Jurkat (calculated MW of 66.4kD according to NP_005564.1). Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: LMNB1 / Lamin B1 (LMNB1 Products)

Synonyms: MGC52550 antibody, Lamin-L(I) antibody, lamin-b antibody, lmn antibody, lmn2 antibody, lmnb antibody, LMNB1 antibody, ADLD antibody, LMN antibody, LMN2 antibody, LMNB antibody, fc06g01 antibody, wu:fc06g01 antibody, lamin B1 L homeolog antibody, lamin B1 antibody, lmnb1.L antibody, lmnb1 antibody, LMNB1 antibody, Lmnb1 antibody

Background: Name/Gene ID: LMNB1

Synonyms: LMNB1, ADLD, Lamin B1, Lamin-B1, LMN, LMNB, LMN2

Gene ID: 4001

NCBI Accession: NP_005564, NP_001185486

Pathways: Apoptosis, Caspase Cascade in Apoptosis