NR3C2 antibody (AA 966-984)

Catalog No. ABIN2625400

The Rabbit Polyclonal anti-NR3C2 antibody (ABIN2625400) specifically detects NR3C2 in WB. The antibody is reactive with Human, Rat, Mouse, Horse, Monkey, Chicken and Bat samples.

Quick Overview for NR3C2 antibody (AA 966-984) (ABIN2625400)

Target: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Reactivity: Human, Rat, Mouse, Horse, Monkey, Chicken, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR3C2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NR3C2 Antibody

Binding Specificity: AA 966-984

Specificity: Ubiquitous. Highly expressed in distal tubules, convoluted tubules and cortical collecting duct in kidney, and in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis and in colon enterocytes. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NR3C2 (966-984aa DQLPKVESGNAKPLYFHRK), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for NR3C2

Target: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Alternative Name: Mineralocorticoid Receptor

Background: Name/Gene ID: NR3C2
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR

Gene ID: 4306

Pathways: ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway