NR3C2 antibody
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- Target See all NR3C2 Antibodies
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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Reactivity
- Human, Rat, Rabbit, Chicken
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NR3C2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Recognizes human MR (mineralocorticoid receptor). Detects a band of ~116kD by Western Blot. Species cross-reactivity: Rat, rabbit and chicken.
- Purification
- Protein G purified
- Immunogen
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Aldosterone.
Type of Immunogen: Hapten - Clone
- H10E4C9F
- Isotype
- IgG1
- Top Product
- Discover our top product NR3C2 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (1:50), WB (1:250)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3162 was determined to be 1:50. Function: Blocks the binding of aldosterone to the MR. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.2, 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).
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LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).
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- Target
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Alternative Name
- Mineralocorticoid Receptor (NR3C2 Products)
- Synonyms
- mr antibody, si:ch211-189l17.1 antibody, LOC100302443 antibody, NR3C2 antibody, LOC443144 antibody, MLR antibody, MR antibody, MCR antibody, NR3C2VIT antibody, Mlr antibody, mlr antibody, nuclear receptor subfamily 3, group C, member 2 antibody, nuclear receptor subfamily 3 group C member 2 antibody, mineralocorticoid receptor antibody, nuclear receptor subfamily 3 group C member 2 L homeolog antibody, nr3c2 antibody, NR3C2 antibody, LOC443144 antibody, Nr3c2 antibody, nr3c2.L antibody
- Background
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Name/Gene ID: NR3C2
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR - Gene ID
- 4306
- UniProt
- P08235
- Pathways
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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