CDKN2B antibody

Catalog No. ABIN264330

The Mouse Monoclonal anti-CDKN2B antibody (Clone DCS-114-1) (ABIN264330) specifically detects CDKN2B in WB, IP and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CDKN2B antibody (ABIN264330)

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN2B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DCS-114-1

Product Details anti-CDKN2B Antibody

Characteristics: Synonyms: p14INK4b, MTS2, p14-INK4b, p15-INK4b, Cyclin-dependent kinase 4 inhibitor B, Multipletumor suppressor 2

Purification: Purified

Immunogen: his-tagged recombinant full length p15 protein recognizing a 15 kDa protein.

Isotype: IgG1

Application Details

Application Notes: Western Blot (1-5 μg). Immunoprecipitation: coprecipitates cdk4/cdk6. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Alternative Name: CDKN2B / p15INK4b

Background: The p15ink4b Multiple tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b

Gene ID: 1030

UniProt: P42772

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases