RYK antibody

Catalog No. ABIN264516

The Mouse Monoclonal anti-RYK antibody (Clone F35 P7 D7 F5) (ABIN264516) specifically detects RYK in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RYK antibody (ABIN264516)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RYK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: F35 P7 D7 F5

Product Details anti-RYK Antibody

Specificity: This antibody reacts to Receptor-Like Tyrosine Kinase.

Characteristics: Synonyms: JTK5A

Purification: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the human RYK protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and rat.

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1-5 μg/mL. Positive Control: HCT116 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: Tyrosine-Protein Kinase RYK

Background: RYK (Receptor like Tyrosine kinase 1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and it contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine kinase related domain. RYK is expressed in nestin positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O2A progenitor cells, and type 2 astrocytes in developing CNS.Synonyms: JTK5A

Gene ID: 6259

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size