MARK3 antibody

Catalog No. ABIN264979

This Sheep Polyclonal antibody specifically detects MARK3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for MARK3 antibody (ABIN264979)

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MARK3 Antibody

Specificity: This antibody reacts to C-TAK1.

Purification: Purified

Immunogen: Recombinant, full-length His-tagged human C-TAK1 produced in E. Coli.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1 to 5 μg/mL. Detects c-tak1 in RKO and HCT116 cell lysatesPOSITIVE CONTROL: Recombinant His-tagged C-TAK1 protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3

Background: C-TAK1 (Cdc25C associated protein kinase) is a ubiquitously expressed protein kinase found in human tissues and cell lines and can phosphorylate Cdc25C on serine 216 in vitro. C-TAK1 is distinct from the DNA damage checkpoint kinase Chk1 and may regulate interactions between Cdc25C and 14-3-3 in vivo by phosphorylating Cdc25C at serine 216.Synonyms: C-TAK1, CTAK1, Cdc25C-associated protein kinase 1, MAP/microtubule affinity-regulating kinase 3, PAR-1, STK10, Serine/threonine-protein kinase p78

Gene ID: 4140

NCBI Accession: NP_001122390

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interactome