SSRP1 antibody (N-Term)
Quick Overview for SSRP1 antibody (N-Term) (ABIN265056)
Target
See all SSRP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-242, N-Term
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Specificity
- This antibody reacts to FACT complex subunit SSRP1.
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Purification
- Purified
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Immunogen
- Recombinant protein consisting of amino acids 1-242 of the human SSRP1 protein.
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Isotype
- IgG
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Application Notes
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Western Blot: 5 - 10 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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Alternative Name
- SSRP1 / FACT80
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Background
- SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.Synonyms: Chromatin-specific transcription elongation factor 80 kDa subunit, FACT 80 kDa subunit, FACT complex subunit SSRP1, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160
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Gene ID
- 6749
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NCBI Accession
- NP_003137
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UniProt
- Q08945
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Pathways
- Chromatin Binding
Target
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