CD47 antibody (Alexa Fluor 647)

Catalog No. ABIN2657806

The Rat Monoclonal anti-CD47 antibody has been validated for ELISA (Capture). It is suitable to detect CD47 in samples from Mouse.

Quick Overview for CD47 antibody (Alexa Fluor 647) (ABIN2657806)

Target: CD47

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD47 antibody is conjugated to Alexa Fluor 647

Application: ELISA (Capture)

Clone: Miap301

Product Details anti-CD47 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD47

Target: CD47

Alternative Name: CD47

Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.