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CD47 antibody (CD47) (AA 241-323) Primary Antibody

CD47 Reactivity: Mouse, Rat ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN739530
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    CD47
    Binding Specificity
    • 15
    • 11
    • 9
    • 9
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 241-323
    Reactivity
    • 158
    • 61
    • 31
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 90
    • 82
    • 1
    • 1
    Rabbit
    Clonality
    • 91
    • 82
    Polyclonal
    Conjugate
    • 68
    • 14
    • 11
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This CD47 antibody is un-conjugated
    Application
    • 104
    • 67
    • 54
    • 44
    • 31
    • 28
    • 25
    • 19
    • 15
    • 15
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Human, Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CD47/MER6
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Miedel, Dishowitz, Myers, Dopkin, Yu, Miclau, Marcucio, Ahn, Hankenson: "Disruption of thrombospondin-2 accelerates ischemic fracture healing." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 31, Issue 6, pp. 935-43, 2013 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: tibia

  • Target
    CD47
    Alternative Name
    CD47/MER6 (CD47 Antibody Abstract)
    Synonyms
    IAP, MER6, OA3, 9130415E20Rik, AA407862, AI848868, AW108519, B430305P08Rik, Itgp, CD47/IAP, alkaline phosphatase, intestinal, CD47 molecule, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), Cd47 molecule, ALPI, CD47, Cd47
    Background

    Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

    Subcellular location: Cell membrane

    Synonyms: IAP, OA3, MER6, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6, CD47

    Gene ID
    961
    UniProt
    Q08722
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