TIMD4 antibody (Alexa Fluor 647)

Catalog No. ABIN2658021

This Rat Monoclonal antibody specifically detects TIMD4 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for TIMD4 antibody (Alexa Fluor 647) (ABIN2658021)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TIMD4 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: F31-5G3

Product Details anti-TIMD4 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Alternative Name: Tim-4

Background: TIM4 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed on antigen-presenting cells and not on T cells.TIM4 binds to TIM1 to promote T cell proliferation by enhancing cell division and reducing apoptosis.TIM4 bind to phosphatidylserine through its FG-CC' binding cleft in the N-terminal IgV domain to facilitate the clearance of apoptotic cells or bodies.

Pathways: Cancer Immune Checkpoints