JAG1 antibody (APC)

Catalog No. ABIN2658199

The Armenian Hamster Monoclonal anti-JAG1 antibody is suitable to detect JAG1 in samples from Mouse. It has been validated for CyTOF and ELISA (Capture).

Quick Overview for JAG1 antibody (APC) (ABIN2658199)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This JAG1 antibody is conjugated to APC

Application: Cytometry by Time of Flight (CyTOF), ELISA (Capture)

Clone: HMJ1-29

Product Details anti-JAG1 Antibody (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: CD339

Background: CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Pathways: Notch Signaling, Stem Cell Maintenance