CLEC12A antibody (APC)

Catalog No. ABIN2658220

Product Details anti-CLEC12A Antibody (APC)

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CLEC12A antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: 5D3-CLEC12A

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CLEC12A

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Alternative Name: CD371 (CLEC12A Products)

Synonyms: MGC179455 antibody, CLL-1 antibody, CLL1 antibody, DCAL-2 antibody, MICL antibody, D230024O04 antibody, KLRL1 antibody, Micl antibody, C-type lectin domain family 12 member A antibody, C-type lectin domain family 12, member a antibody, C-type lectin domain family 12, member A antibody, CLEC12A antibody, Clec12a antibody

Background: CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8 + dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.