Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD46 antibody (PE-Cy7)

The Mouse Monoclonal anti-CD46 antibody has been validated for FACS. It is suitable to detect CD46 in samples from Human.
Catalog No. ABIN2659285

Quick Overview for CD46 antibody (PE-Cy7) (ABIN2659285)

Target

See all CD46 Antibodies
CD46

Reactivity

  • 131
  • 37
  • 23
  • 11
  • 10
  • 3
Human

Host

  • 91
  • 63
  • 2
  • 1
Mouse

Clonality

  • 79
  • 78
Monoclonal

Conjugate

  • 64
  • 17
  • 14
  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is conjugated to PE-Cy7

Application

  • 93
  • 87
  • 42
  • 41
  • 39
  • 24
  • 22
  • 14
  • 14
  • 9
  • 8
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

TRA-2-10
  • Purification

    The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CD46

    Alternative Name

    CD46

    Background

    CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.

    Pathways

    Regulation of Actin Filament Polymerization
You are here:
Chat with us!