TNFRSF4 antibody (PerCP-Cy5.5)

Catalog No. ABIN2659952

The PerCP-Cy5.5-conjugated Mouse Monoclonal anti-TNFRSF4 antibody (Clone Ber-ACT35 (ACT35)) (ABIN2659952) specifically detects TNFRSF4 in FACS. The antibody is reactive with Human samples.

Quick Overview for TNFRSF4 antibody (PerCP-Cy5.5) (ABIN2659952)

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF4 antibody is conjugated to PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: Ber-ACT35 (ACT35)

Product Details anti-TNFRSF4 Antibody (PerCP-Cy5.5)

Cross-Reactivity: Chimpanzee

Purification: The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Alternative Name: CD134

Background: CD134, also known as OX40 and TNFRSF14, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints