Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL15RA antibody (Biotin)

IL15RA Reactivity: Human WB, IHC, FACS, CMCD, Dep, IP Host: Mouse Monoclonal JM7A4 Biotin
Catalog No. ABIN2660994
  • Target See all IL15RA Antibodies
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Reactivity
    • 43
    • 28
    • 15
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 4
    • 2
    • 2
    Mouse
    Clonality
    • 40
    • 7
    Monoclonal
    Conjugate
    • 22
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL15RA antibody is conjugated to Biotin
    Application
    • 44
    • 22
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Complement Mediated Cell Depletion (CMCD), Depletion (Dep), Immunoprecipitation (IP)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    JM7A4
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product IL15RA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Alternative Name
    CD215 (IL15RA Products)
    Synonyms
    IL15RA antibody, CD215 antibody, AA690181 antibody, IL-15RA antibody, interleukin 15 receptor subunit alpha antibody, interleukin 15 receptor, alpha chain antibody, IL15RA antibody, Il15ra antibody
    Background
    IL-15 receptor α (IL-15Rα) is a cytokine receptor with the structural homology to IL-2Rα (CD25). Both α receptors contain a group of β sandwich protein called sushi domains. Similar to IL-2Rα, IL-15Rα is able to form a heterotrimer with their β chain (CD122) and common γ chain (γc, CD132). But unlike IL-2Rα subunit, IL-15Rα itself binds to IL-15 with equivalent high affinity compared with the heterotrimeric complex. IL-15Rα is expressed as soluble or transmembrane forms by variety cells, such as activated monocytes, dendritic cells, CD8+ memory T cells, NK or NKT cells. IL-15Rα by itself forms stable complexes with IL-15 on cell surface and presents IL-15 in trans to neighboring cells. IL-15, like IL-2, is a pleiotropic four-helix bundle cytokine and plays a key role in promoting T and B cell survival and proliferation, preferentially in memory CD8+ T cell proliferation, and NK/NKT cell development.
    Pathways
    JAK-STAT Signaling
You are here:
Support