TLR10 antibody (AA 20-474) (PE)

Catalog No. ABIN2662578

The PE-conjugated Mouse Monoclonal anti-TLR10 antibody (Clone 3C10C5) (ABIN2662578) specifically detects TLR10 in ICFC. The antibody is reactive with Human samples.

Quick Overview for TLR10 antibody (AA 20-474) (PE) (ABIN2662578)

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR10 antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: 3C10C5

Product Details anti-TLR10 Antibody (PE)

Binding Specificity: AA 20-474

Cross-Reactivity: Cynomolgus

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Immunogen: AA 20-474 (NP_001017388)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Alternative Name: CD290

Background: CD290, also known as TLR10, is a 91-100 kD glycosylated protein belonging to the toll-like receptor family. It is expressed on B cell, Treg cells, and plasmacytoid dendritic cells but absent on T cells, particularly non-Treg and granulocytes. It can interact with MyD88 and plays an important role in innate immunity and pattern recognition.

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades