TLR10 antibody (AA 600-650)

Catalog No. ABIN6990453

The Rabbit Polyclonal anti-TLR10 antibody (ABIN6990453) specifically detects TLR10 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for TLR10 antibody (AA 600-650) (ABIN6990453)

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TLR10 Antibody

Binding Specificity: AA 600-650

Purification: TLR10 Antibody is Ion exchange chromatography purified.

Immunogen: TLR10 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human TLR10. The immunogen is located within amino acids 600 - 650 of TLR10.

Isotype: IgG

Application Details

Application Notes: TLR10 antibody can be used for detection of TLR10 by Western blot at 0.5 to 1 μ,g/mL. Despite its predicted size of ~90 kDa, a band correpsonding to TLR10 is observed at ~75 kDa in immunoblot assays. For immunofluorescence start at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TLR10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Alternative Name: TLR10

Background: TLR10 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues. Most recently genetic variation in TLR10 has been associated with contributing to asthma risk. It should be noted that TLR10 exists in mice only as a pseudogene.

Gene ID: 81793

UniProt: Q9BXR5

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades