SCARB1 antibody

Catalog No. ABIN2664631

The Mouse Monoclonal anti-SCARB1 antibody is suitable to detect SCARB1 in samples from Human. It has been validated for FACS.

Quick Overview for SCARB1 antibody (ABIN2664631)

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SCARB1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: M1B9

Product Details anti-SCARB1 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for SCARB1

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Alternative Name: CD36L1

Background: Scavenger receptor class B type I (SCARB1), also known as CD36L1, is an integral membrane protein found in numerous cell types and tissues that is mainly expressed in the liver and the adrenal glands. Its primary function is facilitating the uptake of cholesteryl esters from high-density lipoproteins (HDL) due to its high affinity to HDL. This function serves to lower the risk of development of atherosclerosis. SCARB1 is also able to bind to other lipoproteins such as LDL, OxLDL, and VLDL. SCARB1 is also likely to be involved in pathogen recognition through its recognition of mycobacteria and other viral proteins and regulates vitamin E levels in the tissue.

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome