EPH Receptor A2 antibody

Catalog No. ABIN2664953

The Mouse Monoclonal anti-EPH Receptor A2 antibody (Clone SHM16) (ABIN2664953) specifically detects EPH Receptor A2 in FACS and ICFC. The antibody is reactive with Human samples.

Quick Overview for EPH Receptor A2 antibody (ABIN2664953)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: SHM16

Product Details anti-EPH Receptor A2 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EphA2

Background: Ephrin receptor A2 (EphA2), also known as Eck, is a 130 kD type I transmembrane glycoprotein which belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA2 is expressed on epithelial cells, keratinocytes, dendritic/Langerhans cells and melanocytes. It has also been observed in breast, cervical, ovarian, prostate, colon, skin and lung cancers. EphA2 is an oncoprotein which is an essential survival factor for many melanomas. EphA2 plays an important role in angiogenesis and tumor neovascularization through interaction with ephrin-A1, -A3, -A4 and -A5.

Pathways: RTK Signaling