IRF5 antibody
Quick Overview for IRF5 antibody (ABIN2666392)
Target
See all IRF5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2b kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Upon receipt, store undiluted between 2°C and 8°C.
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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Alternative Name
- IRF5
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Background
- IRF-5 is a transcription factor belonging to the interferon regulatory factor family. It controls induction of type I IFN genes as well as inflammatory cytokines and chemokines through TLRs and the MyD88-TRAF6 pathway. Several genetic variations of IRF-5 have been reported as a risk factor of Systemic lupus erythematosus (SLE), which is caused by excess IFNα induction.
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Pathways
- TLR Signaling, Autophagy
Target
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