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LEF1 antibody
LEF1
Reactivity: Human
BCA
Host: Mouse
Monoclonal
15H5A18
unconjugated
Product Details anti-LEF1 Antibody
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Target
See all LEF1 Antibodies
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
Reactivity
All reactivities for LEF1 antibodies
Human
Host
All hosts for LEF1 antibodies
Mouse
Clonality
All clonalities for LEF1 antibodies
Monoclonal
Conjugate
All conjugates for LEF1 antibodies
This LEF1 antibody is un-conjugated
Application
All applications for LEF1 antibodies
Biochemical Assay (BCA)
Clone
15H5A18
Isotype
IgG1 kappa
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Discover our top product LEF1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Upon receipt, store undiluted between 2°C and 8°C.
Target Details for LEF1
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Target
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
Alternative Name
LEF1 (LEF1 Products )
Synonyms
LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
Background
Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor belonging to the TCF/LEF family. LEF1 was first identified as a protein binding to TCR- α enhancer and upregulates expression of T-cell antigen receptor α chain. LEF1 is involved in Wnt signaling pathways as a ubiquitous regulator. During Wnt signaling, translocation of β-catenin from the cytosol to the nucleus results in elevation of transcriptional activity of LEF1, which subsequently regulates multiple downstream genes.
Pathways
WNT Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Hormone Metabolic Process , Nuclear Hormone Receptor Binding , Chromatin Binding
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