HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (AA 898-1051)

Details for Product anti-HIPK2 Antibody No. ABIN2668288, Supplier: Log in to see
Antigen
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine kinase
  • homeodomain interacting protein kinase 2 L homeolog
  • HIPK2
  • Smp_000720
  • hipk2
  • hipk2.L
  • Hipk2
Alternatives
anti-Human HIPK2 antibody for Immunohistochemistry
Epitope
AA 898-1051
18
17
11
10
9
7
6
3
3
2
1
1
1
1
Reactivity
Human
102
12
10
3
2
2
2
2
2
1
1
1
1
Host
Mouse
89
13
Clonality
Monoclonal
Conjugate
This HIPK2 antibody is un-conjugated
8
8
8
8
8
4
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
68
66
42
17
14
4
3
3
2
2
Options
Supplier
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Immunogen This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2.
Isotype IgG
Purification Protein G Chromatography
Plasmids, Primers & others Plasmids, Primers & others HIPK2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name HIPK2 (HIPK2 Antibody Abstract)
Background HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity.
Molecular Weight 130 kDa
Gene ID 28996
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 μg/μL
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months
Product cited in: Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." in: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, 2006 (PubMed).

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