Rpb1 CTD antibody (pSer2, Ser2)
-
- Target See all Rpb1 CTD products
- Rpb1 CTD (RNA Polymerase II CTD)
-
Binding Specificity
- pSer2, Ser2
-
Reactivity
- Human, Mouse
-
Host
- Rat
-
Clonality
- Monoclonal
-
Conjugate
- This Rpb1 CTD antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq), Immunoprecipitation (IP)
- Purification
- Protein G Chromatography
- Immunogen
- This RNA pol II CTD pSer2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.
- Clone
- 3E10
- Isotype
- IgG1
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 1 μg/μL
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
-
Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -80 °C
- Storage Comment
- Antibodies in solution can be stored at -80 °C for 2 years.
- Expiry Date
- 6 months
-
-
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3." in: eLife, Vol. 5, (2016) (PubMed).
: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).
: "Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin." in: PLoS genetics, Vol. 11, Issue 3, pp. e1004986, (2015) (PubMed).
: "Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 468-78, (2014) (PubMed).
: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." in: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).
: "Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7." in: Science (New York, N.Y.), Vol. 318, Issue 5857, pp. 1780-2, (2007) (PubMed).
: "
-
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3." in: eLife, Vol. 5, (2016) (PubMed).
-
- Target
- Rpb1 CTD (RNA Polymerase II CTD)
- Alternative Name
- RNA Pol II CTD (Rpb1 CTD Products)
- Molecular Weight
- 240 kDa
- Gene ID
- 5430
-