Rpb1 CTD antibody (pThr4)
Quick Overview for Rpb1 CTD antibody (pThr4) (ABIN6972631)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr4
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Characteristics
- RNA pol II (RNA polymerase II) is a complex of 12 proteins that participates in transcription, mRNA processing, and transcription-coupled DNA repair. RNA polymerase II is distinguished by its large carboxyl-terminal repeat domain (CTD), composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Polo-like kinase 3 (plk3) has been reported to phosphorylate Thr4 which may be required for transcriptional elongation. RNA pol II CTD phospho Thr4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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Purification
- Protein A Chromatography
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Immunogen
- This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
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Isotype
- IgG
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anti-RNA Polymerase II CTD (pSer5) antibody
Reactivity: Human, Mouse WB, ChIP, ChIP-seq Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II CTD (pSer5), (Ser5) antibodyReactivity: Human, Mouse WB, ChIP, ChIP-seq Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II CTD (pSer5), (Ser5) antibodyReactivity: Human, Mouse WB, IF, ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II CTD (pSer7) antibodyReactivity: Human WB, IF, ICC Host: Rat Monoclonal 3D4A12 unconjugated
anti-RNA Polymerase II CTD (pSer2) antibodyReactivity: Human WB, IF, ICC Host: Rat Monoclonal 3E7C7 unconjugated
anti-RNA Polymerase II CTD (pSer5) antibodyReactivity: Human WB, IF, ICC Host: Rat Monoclonal 1H4B6 unconjugated
anti-RNA Polymerase II CTD (pSer5) antibodyReactivity: Human, Saccharomyces cerevisiae WB, IF, ICC, ELISA, FACS Host: Mouse Monoclonal 8A7 unconjugated
anti-RNA Polymerase II CTD (pTyr1) antibodyReactivity: Human WB, IF, ELISA Host: Mouse Monoclonal unconjugated Recombinant Antibody
anti-RNA Polymerase II CTD (pSer5), (Ser5) antibodyReactivity: Human WB, IF, ICC, ChIP, ChIP-seq, IP Host: Rat Monoclonal 3E8 unconjugated
anti-RNA Polymerase II CTD (pSer2), (Ser2) antibodyReactivity: Human, Mouse WB, IF, ICC, ChIP, ChIP-seq, IP Host: Rat Monoclonal 3E10 unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Rpb1 CTD (RNA Polymerase II CTD)
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Alternative Name
- RNA pol II CTD
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Molecular Weight
- 240 kDa
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NCBI Accession
- NP_000928
Target
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