ASCL1 antibody

Catalog No. ABIN2668587

This Mouse Monoclonal antibody specifically detects ASCL1 in WB and IHC. It exhibits reactivity toward Mouse and Rat. It has been mentioned in 3+ publications

Quick Overview for ASCL1 antibody (ABIN2668587)

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ASCL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 24B7-2D11-1

Product Details anti-ASCL1 Antibody

Purification: Protein A Chromatography

Immunogen: This MASH1 antibody was raised against a full-length protein corresponding to rat MASH1.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-ASCL1 antibody (ABIN2668587)

Ivaniutsin, Chen, Mason, Price, Pratt: "Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex." in: Neural development, Vol. 4, Issue 1, pp. 3, (2009) (PubMed).

Ralston, Chiriboga, Nonaka: "MASH1: a useful marker in differentiating pulmonary small cell carcinoma from Merkel cell carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 11, pp. 1357-62, (2008) (PubMed).

Lo, Johnson, Wuenschell, Saito, Anderson: "Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells." in: Genes & development, Vol. 5, Issue 9, pp. 1524-37, (1991) (PubMed).

Target Details for ASCL1

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Alternative Name: MASH1

Molecular Weight: 34 kDa

Gene ID: 64186

Pathways: Dopaminergic Neurogenesis