MAZ antibody

Catalog No. ABIN2668733

Cited in 2+ publications. The Mouse Monoclonal anti-MAZ antibody (Clone 133) (ABIN2668733) specifically detects MAZ in WB, ChIP and SSA. The antibody is reactive with Human samples.

Quick Overview for MAZ antibody (ABIN2668733)

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAZ antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Supershift Assay (SSA)

Clone: 133

Product Details anti-MAZ Antibody

Purpose: MAZ antibody (mAb) (Clone 133)

Purification: Protein G Chromatography

Immunogen: This MAZ antibody was raised against recombinant human MAZ protein.

Isotype: IgG

Application Details

Application Notes: WB This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91205.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-MAZ antibody (ABIN2668733)

Himeda, Ranish, Hauschka: "Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes." in: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6521-35, (2008) (PubMed).

Ashfield, Patel, Bossone, Brown, Campbell, Marcu, Proudfoot: "MAZ-dependent termination between closely spaced human complement genes." in: The EMBO journal, Vol. 13, Issue 23, pp. 5656-67, (1995) (PubMed).

Target Details for MAZ

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Alternative Name: Maz

Background: MAZ (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. MAZ binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. MAZ also participates in skeletal muscle development through the activation of several skeletal muscle-specific genes. MAZ has also been reported to drive tumor-specific expression of PPAR-gamma in breast cancer cells.

Molecular Weight: 55 kDa

Gene ID: 4150

NCBI Accession: NP_002374

Pathways: Chromatin Binding