CD46 antibody

Catalog No. ABIN2689293

The Mouse Monoclonal anti-CD46 antibody has been validated for FACS and FM. It is suitable to detect CD46 in samples from Human.

Quick Overview for CD46 antibody (ABIN2689293)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Clone: E4-3

Product Details anti-CD46 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with membrane cofactor protein (MCP), a type I membrane glycoprotein composed of two non-disulfide linked α (66 kDa) and β(56 kDa) chains expressed on lymphocytes, monocytes and granulocytes. It is not expressed on erythrocytes or platelets. There are four isoforms of the dimer which function as complement regulatory factors. CD46 promotes the enzymatic degradation of activated C3b and/or C4b deposited on host cells. It also serves as the measles virus receptor. Profile peripheral blood lymphocytes analyzed on a FACScan .

BD Pharmingen™ Purified Mouse Anti Human CD46 - Purified - Clone E4.3 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background: Synonyms: MCP

Pathways: Regulation of Actin Filament Polymerization