IL-5 antibody

Catalog No. ABIN2689771

Cited in 5+ publications. The Rat Monoclonal anti-IL-5 antibody (Clone JES1) (ABIN2689771) specifically detects IL-5 in WB, ELISA and InhibAb. The antibody is reactive with Human samples.

Quick Overview for IL-5 antibody (ABIN2689771)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Clone: JES1

Product Details anti-IL-5 Antibody

Characteristics: The JES1-39D10 antibody reacts with human interleukin-5 (IL-5). The immunogen used to generate the JES1-39D10 hybridoma was COS-expressed recombinant human IL-5. This is a neutralizing antibody. This antibody is routinely tested by ELISA. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Rat Anti-Human IL-5 - Purified - Clone JES1-39D10 - Isotype Rat IgG2a - Reactivity Hu - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant human IL-5

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-IL-5 antibody (ABIN2689771)

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Jung, Schauer, Rieger, Wagner, Einsle, Neumann, Heusser: "Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells." in: European journal of immunology, Vol. 25, Issue 8, pp. 2413-6, (1995) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Butterfield, Leiferman, Abrams, Silver, Bower, Gonchoroff, Gleich: "Elevated serum levels of interleukin-5 in patients with the syndrome of episodic angioedema and eosinophilia." in: Blood, Vol. 79, Issue 3, pp. 688-92, (1992) (PubMed).

Limaye, Abrams, Silver, Awadzi, Francis, Ottesen, Nutman: "Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis." in: The Journal of clinical investigation, Vol. 88, Issue 4, pp. 1418-21, (1991) (PubMed).

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL-5

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour