JAK2 antibody (pTyr1007)

Catalog No. ABIN7296072

The Rabbit Polyclonal anti-JAK2 antibody is suitable to detect JAK2 in samples from Human, Rat, Mouse, Zebrafish (Danio rerio), Pig and Chicken. It has been validated for WB, IHC and IF.

Quick Overview for JAK2 antibody (pTyr1007) (ABIN7296072)

Target: JAK2 (Janus Kinase 2 (JAK2))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-JAK2 Antibody

Binding Specificity: pTyr1007

Purpose: Rabbit polyclonal antibody to JAK2 (Phospho-Y1007)

Specificity: Recognizes endogenous levels of JAK2 protein only when phosphorylated at Y1007.

Characteristics: Rabbit polyclonal antibody to JAK2 (pY1007)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y1007 of human JAK2 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/200), IF/IC (1/50 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for JAK2

Target: JAK2 (Janus Kinase 2 (JAK2))

Alternative Name: JAK2

Background: Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2

Gene ID: 3717, 16452, 24514

UniProt: O60674

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response