EIF2AK2 antibody (pThr451)

Catalog No. ABIN7299422

The Rabbit Polyclonal anti-EIF2AK2 antibody (ABIN7299422) specifically detects EIF2AK2 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for EIF2AK2 antibody (pThr451) (ABIN7299422)

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2AK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EIF2AK2 Antibody

Binding Specificity: pThr451

Purpose: Rabbit polyclonal antibody to PKR (Phospho-T451)

Specificity: Recognizes endogenous levels of PKR protein only when phosphorylated at T451.

Characteristics: Rabbit polyclonal antibody to PKR (pT451)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T451 of human PKR protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Alternative Name: PKR

Background: PKR, PRKR, Interferon-induced, double-stranded RNA-activated protein kinase, Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated, PKR, Tyrosine-protein kinase EIF2AK2, p68 kinase

Gene ID: 5610, 19106

UniProt: P19525

Pathways: DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C