Phospholipase C gamma 1 antibody (pTyr1253)

Catalog No. ABIN7296608

The Rabbit Polyclonal anti-Phospholipase C gamma 1 antibody is suitable to detect Phospholipase C gamma 1 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and IF.

Quick Overview for Phospholipase C gamma 1 antibody (pTyr1253) (ABIN7296608)

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C gamma 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Phospholipase C gamma 1 Antibody

Binding Specificity: pTyr1253

Purpose: Rabbit polyclonal antibody to PLC gamma 1 (Phospho-Y1253)

Specificity: Recognizes endogenous levels of PLC gamma 1 protein only when phosphorylated at Y1253.

Characteristics: Rabbit polyclonal antibody to PLC gamma 1 (pY1253)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y1253 of human PLC gamma 1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Phospholipase C gamma 1

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Alternative Name: PLC gamma 1

Background: PLC1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1

Gene ID: 5335, 18803, 25738

UniProt: P19174

Pathways: RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling