MEK1 antibody (pSer222, pSer226)

Catalog No. ABIN7299796

This Rabbit Polyclonal antibody specifically detects MEK1 in WB, IHC, IF and IP. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Chicken and Zebrafish (Danio rerio).

Quick Overview for MEK1 antibody (pSer222, pSer226) (ABIN7299796)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Chicken, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-MEK1 Antibody

Binding Specificity: pSer222, pSer226

Purpose: Rabbit polyclonal antibody to MKK1/2 (Phospho-S222/226)

Specificity: Recognizes endogenous levels of MKK1/2 protein only when phosphorylated at S222/226.

Characteristics: Rabbit polyclonal antibody to MKK1/2 (pS222/226)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S222/226 of human MKK1/2 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500), IP (1/10 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: MKK1/2

Target Type: Chemical

Background: MAP2K1, MEK1, PRKMK1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K2, MEK2, MKK2, PRKMK2, Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2

Gene ID: 5604, 26395, 170851

UniProt: Q02750

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling